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Cho Laboratory
Cho Laboratory
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Welcome to the group

We are an multidisciplinary team of scientists & engineers interested in how our cells interact with each other and with their physical microenvironment, particularly in the context of fibrosis—‘scarring’ of tissue that contributes to a vast range of human diseases.

Systems mechanobiology &
regenerative engineering

We take a systems approach to investigate mechanisms that drive fibrotic remodeling and tissue regeneration by integrating (i) cell & molecular biology, (ii) organoid and biomaterials engineering, and (iii) data science.

Our mission

Our long-term goal is to develop new precision therapies for treating fibrosis-associated diseases and conditions, which span cardiovascular disease, cancer, and aging.

Learn more about our work

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Latest Publications

Sangkyun Cho, PhD, Siyeon Rhee, Christopher Madl, Arianne Caudal, Dilip Thomas, Hyeonyu Kim, Ana Kojic, Hye Sook Shin, Abhay Mahajan, James Jahng, Xi Wang, Phung Thai, David Paik, Mingqiang Wang, McKay Mullen, Natalie Baker, Jeremy Leitz, Souhrid Mukherjee, Virginia Winn, Y Joseph Woo, Helen Blau, Joseph Wu. Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis. Nature, 2025.
DOI
Sangkyun Cho, PhD, Dennis Discher, Kam Leong, Gordana Vunjak-Novakovic, Joseph Wu. Challenges and opportunities for the next generation of cardiovascular tissue engineering. Nat Methods, 2022.
DOI
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Latest News

Krystal, Stacia, and Neri join as the first PhD students of the Cho Lab!

We had our first ever lab meeting on October 30th, 2025, with our newest founding members.

Oct 30, 2025 1 min read
Krystal, Stacia, and Neri join as the first PhD students of the Cho Lab!
Hwan joins the lab as the first lab member and postdoctoral fellow

Hwan joins us from Penn State University, where he completed his PhD in Biomedical Engineering. Welcome to Hopkins, Hwan!

Oct 20, 2025 1 min read
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  Meet the team →

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