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Cho Laboratory
Cho Laboratory
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Welcome to the group

We are a team of scientists & engineers that studies how our cells interact with each other and with their physical microenvironment, particularly in the context of fibrosis—‘scarring’ of tissue that contributes to a vast range of human diseases.

Systems mechanobiology &
regenerative engineering

We take a systems approach to investigate mechanisms that drive tissue regeneration and fibrotic remodeling by integrating (i) molecular biology, (ii)tissue and biomaterials engineering, and (iii) data science.

Our mission

Our long-term goal is to develop new precision therapies for treating fibrosis-associated diseases and conditions, which span cardiovascular disease, cancer, and aging.

Learn more about our work

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Latest Publications

Sangkyun Cho, Siyeon Rhee, Christopher Madl, Arianne Caudal, Dilip Thomas, Hyeonyu Kim, Ana Kojic, Hye Sook Shin, Abhay Mahajan, James Jahng, Xi Wang, Phung Thai, David Paik, Mingqiang Wang, McKay Mullen, Natalie Baker, Jeremy Leitz, Souhrid Mukherjee, Virginia Winn, Y Joseph Woo, Helen Blau, Joseph Wu. Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis. Nature, 2025.
DOI
Sangkyun Cho, Dennis Discher, Kam Leong, Gordana Vunjak-Novakovic, Joseph Wu. Challenges and opportunities for the next generation of cardiovascular tissue engineering. Nat Methods, 2022.
DOI
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Latest News

The Cho Lab officially launched at Johns Hopkins!

We will be based on the third floor of Croft Hall (Institute for NanoBioTechnology, INBT) on the Johns Hopkins Homewood campus, with a satellite lab at the School of Medicine.

Aug 25, 2025 1 min read
The Cho Lab officially launched at Johns Hopkins!
We received the NIH Pathway to Independence Award (R00) to jump-start our research program

This federal grant is an extension of our K99 Award and will provide funding support for three years.

Aug 1, 2025 1 min read
We received the NIH Pathway to Independence Award (R00) to jump-start our research program
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