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Cho Laboratory
Cho Laboratory
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Welcome

We are a multidisciplinary team of scientists & engineers interested in how our cells interact with each other and with their physical microenvironment, particularly in the context of fibrosis—‘scarring’ of tissue that contributes to a vast range of human diseases.

Systems mechanobiology &
regenerative engineering

We take a systems approach to investigate mechanisms that drive fibrotic remodeling and tissue regeneration by integrating (i) cell & molecular biology, (ii) organoid and biomaterials engineering, and (iii) data science.

Our mission

Our long-term goal is to develop new precision therapies for treating fibrosis-associated diseases, which span cardiovascular disease, cancer, and aging.

Learn more about our work

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Latest Publications

Sangkyun Cho, PhD, Siyeon Rhee, Christopher Madl, Arianne Caudal, Dilip Thomas, Hyeonyu Kim, Ana Kojic, Hye Sook Shin, Abhay Mahajan, James Jahng, Xi Wang, Phung Thai, David Paik, Mingqiang Wang, McKay Mullen, Natalie Baker, Jeremy Leitz, Souhrid Mukherjee, Virginia Winn, Y Joseph Woo, Helen Blau, Joseph Wu. Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis. Nature, 2025.
DOI
Sangkyun Cho, PhD, David Paik, Joseph Wu. An extracellular matrix paradox in myocardial scar formation. 0001.
Na Yeon Kim, Hyojung Jo, Chloe Becker, Isaiah Soicher, Yeqing Ni, Sangkyun Cho, PhD, Hyeonyu Kim. Cardiac mechanotransduction from development to disease. 0001.
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Latest News

Dr. Cho wins the 2026 KBMES Young Innovator Award

The KBMES Young Innovator Award recognizes tenure-track assistant professors who have demonstrated outstanding achievements in biomedical research and teaching.

Aug 30, 2026 1 min read
Dr. Cho wins the 2026 KBMES Young Innovator Award
Crabs with the Lab!

We celebrated Hwan’s and Krystal’s birthdays with Maryland crabs and waterfront views at Nick’s Fish House.

Aug 27, 2026 1 min read
Crabs with the Lab!
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  Meet the team →

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