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Jerome Irianto

Scaling concepts in omics - Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis
Mechanosensing by the lamina protects against nuclear Rupture, DNA Damage, and cell-cycle Arrest
Nuclear mechanosensing
Nuclear rupture at sites of high curvature compromises retention of DNA repair factors
Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A, C in iPS-derived mesenchymal stem cells
SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors
Mechanosensing by the nucleus: From pathways to scaling relationships
Matrix elasticity regulates lamin-A,C phosphorylation and turnover with feedback to actomyosin

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